Description
Gamascab® Cream is manufactured by Nulife Pharmaceuticals. This cream is indicated as a second line therapy for scabies or lice infestations in those patients who cannot tolerate safer anti-parasitic medications or have failed to response to first line treatments. In addition to killing already existing on the skin insects, Gamascab® Cream also damages their eggs, therefore stops parasitic growth. Gamascab® Cream should be used with caution and under medical supervision.
The key ingredient of Gamascab® Cream is Lindane, an organochlorine insecticide that has been used as a treatment for certain parasitic skin infections.
Indications:
- scabies (infestation with Sarcoptes scabiei);
- pubic lice (Phthirus pubis).
MOA (mechanism of action):
Lindane is an anti-insect agent of organochloride origin with strong parasiticidal action. It kills parasites by getting directly through their exoskeleton and ova. There, Lindane blocks the gamma-aminobutyric acid (GABA) receptor. The main role of GABA is to reduce neuronal excitability in the nervous system. When GABA receptor is blocked, the nervous system of an insect replies with hyperexcitation, that leads to paralysis and death.
Dosage
Gamascab® Cream should be used with caution and under medical supervision.
Gamascab® Cream should be applied one time only.
Make sure your skin is clean, dry, and cool prior to applying Gamascab® Cream. Do not take hot bath or shower before the Gamascab® Cream application.
If you are applying Gamascab® Cream to someone else, use protective gloves made of nitrile, latex with neoprene, or sheer vinyl. Do not use natural latex gloves as Gamascab® Cream ingredients may destroy it.
Remnants of dead scabies or lice and their eggs may cause itching after the Gamascab® Cream application. This does not mean the treatment failed and you should reapply it.
Gamascab® Cream is for external use only. Do not swallow.
Do not apply Gamascab® Cream to the mucosal surfaces, face, eyes, lips, inside of the nose, vagina, penis (urethra) or back passage.
How to use Gamascab® Cream:
1. Wash your hands with soap before the Gamascab® Cream application.
2. Apply the sufficient amount of Gamascab® Cream from your neck to the soles of the feet.
3. Gently rub Gamascab® Cream until absorbed.
4. Make sure that you get the Gamascab® Cream between your fingers and toes, under the fingernails and toenails, wrists armpits, around genital area and buttocks.
5.Put on clean clothes.
6. Do not take shower or bath for 8 hours at least after Gamascab® Cream application.
7. 8-12 hours after Gamascab® Cream application, rinse it thoroughly with soap and put on clean cloth.
How much Gamascab® Cream to use:
Adults and children weighing over 50 kilograms: about 30 grams of cream.
Consult your doctor on how to apply Gamascab® Cream. Use Gamascab® Cream exactly as directed.
Missing a dose
If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not apply a double dose.
Overdose
Do not exceed the doctor's recommended dose. If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.
Storage
Store at a room temperature from 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away the tube after the expiration date. Keep away from children.
