Description
Azee® XL Dry Syrup manufacturer is Cipla. Azee® XL Dry Syrup contains an active ingredient Azithromycin, an antibiotic with bacteriostatic and antimicrobial activity. It is a broad-spectrum macrolide belonging to azalide group.
Indications:
- acute otitis media;
- pharyngitis/tonsillitis as an alternative to first-line therapy in individuals who cannot use first-line therapy;
- sinusitis;
- acute bronchitis;
- community-acquired pneumonia;
- uncomplicated skin and soft tissues infections (furunculosis, pyoderma, impetigo);
- uncomplicated genital infections.
Azee® XL Dry Syrup is not effective against viruses and fungi.
MOA (mechanism of action):
Azithromycin suppresses bacterial protein synthesis, thus it does not allow bacteria to grow and replicate. In such a way, Azithromycin stops the spread of infection and remaining bacteria eventually die. Azithromycin is active against gram-positive bacteria (Methicillin-susceptible Staphylococcus aureus, Streptococcus agalactiae, Penicillin-susceptible Streptococcus pneumoniae, Streptococcus pyogenes (Group A); gram-negative bacteria (Haemophilus influenzae, Moraxella catarrhalis, Neisseria gonorrhoeae, Haemophilus parainfluenzae, Pasteurella multocida; other bacteria (Chlamydophila pneumoniae, Chlamydia trachomatis, Mycoplasma pneumoniae, Legionella pneumophila, Mycobacterium avium, Mycobacterium intracellulare).
Dosage
Preparation
Azee® XL Dry Syrup should be reconstituted to form an oral suspension.
1. Shake the bottle to loosen the powder.
2. Stir the dry powder with a boiled and cooled water. Recap the bottle, and shake it vigorously.
3. If necessary, add more water up to the arrow mark and shake again.
The reconstituted suspension should be consumed within 5 days after preparation. Keep it tightly closed. Shake well before each use. Throw away the unused portion after 5 days.
Children 6 months and above.
For acute otitis media:
One-day treatment course: 30 mg/kg single dose.
Three-day treatment course: 10 mg/kg once a day.
Five-day treatment course: on the first day 10 mg/kg single dose; during 2-5 days 5 mg/kg per day.
For acute bacterial sinusitis:
Three-day treatment course: 10 mg/kg once a day.
Five-day treatment course: on the first day 10 mg/kg single dose; during 2-5 days 5 mg/kg per day.
For community-acquired pneumonia/acute bronchitis:
Three-day treatment course: 10 mg/kg once a day.
Five-day treatment course: on the first day 10 mg/kg single dose; during 2-5 days 5 mg/kg per day.
For uncomplicated skin and soft tissue infections:
Three-day treatment course: 10 mg/kg once a day.
Five-day treatment course: on the first day 10 mg/kg single dose; during 2-5 days 5 mg/kg per day.
Children between 1 year – 2 years.
For pharyngitis/tonsillitis:
Three-day treatment course: 10 or 20 mg/kg with maximal dose 500 mg per day.
Children 2 years and older.
For pharyngitis/tonsillitis:
Three-day treatment course: 10 or 20 mg/kg with maximal dose 500 mg per day.
Five-day treatment course: 12 mg/kg once per day.
Adolescents and older children weighing over 45 kg.
For uncomplicated genital infections:
One-day treatment course: 1000 mg single dose.
Missing a dose
If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose of Azee® XL Dry Syrup to compensate the missed dose.
Overdose
If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.
Storage
Store at a cool temperature between 15 and 20 degrees C (59 and 68 degrees F) and away from excess moisture and heat. Keep it tightly closed. Throw away any unused medicine in 5 days after reconstitution. Keep out of the reach of children.
