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Axalin® Expectorant

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Axalin® Expectorant

Axalin® Expectorant is an oral syrup used to relieve cough due bronchopulmonary disorders including bronchitis, bronchial asthma, and emphysema among others. Possesses muscle relaxing and secretolytic properties. Suitable for adults and children over 2 years of age. Read more

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Description

Axalin® Expectorant is manufactured by Cipla. This syrup contains Ambroxol, Terbutaline, and Guaiphenesin as active ingredients. Axalin® Expectorant is used to relieve the symptoms of air passages (bronchi) and lungs (pulmonary) diseases. Equally effective for productive and unproductive cough.

Indications:

Axalin® Expectorant is indicated to relieve a cough caused by following conditions:

- bronchopulmonary disorders (bronchitis, bronchial asthma, emphysema, etc.) associated with bronchial spasm, mucoid impaction, and problems of expectoration;

- upper respiratory tract infections (epiglottitis , laryngitis, laryngotracheitis, and tracheitis);

- respiratory tract inflammation (tracheobronchitis);

- allergic reactions (e. g., to a change of season or to pets’ dander, skin flakes, saliva, and urine).

The combination of Ambroxol, Terbutaline, and Guaiphenesin also can be used to treat cough occuring due to active or passive smoking.

MOA (mechanism of action):

Ambroxol is a mucoactive drug with secretolytic and secretomotoric properties. It inhibits the Nitric oxide-depending activation of soluble guanylate cyclase associated with inflammation and other disturbances of airways function. Therefore, Ambroxol renews the clearing mechanisms of the respiratory tract which play an important role in the body’s natural defense against infections. It also reduces the adhesion of mucus to the bronchial walls enhancing the protection against irritating agents.

Terbutaline is a selective beta-2 adrenergic agonist with bronchodilatory and tocolytic properties. It is thought to act through increasing the inner levels of cyclic adenosine monophosphate (c-AMP), important biological messengers. Increased c-AMP levels result in the relaxation of bronchial smooth muscle and inhibition of inflammatory mediators.

Guaiphenesin is an expectorant which promotes the secretion of sputum (a mixture of saliva and mucus) by the air passages reducing adhesiveness and surface tension. It makes a cough more productive, but less recurrent. Then Guaiphenesin removes the accumulated secretions from the upper and lower airway. It also thought to have certain muscle relaxing properties.

Dosage

Axalin® Expectorant should be taken by mouth.

The exact dosage as well as course duration should be indicated by your doctor.

Adults and children over 12 years of age: 10-20 ml three times daily.

Children aged 6 to 12 years: 10 ml three times daily.

Children under 6 years of age: 5-10 ml three times daily.

If your cough has not improved after 5 days of Axalin® Expectorant treatment course, stop taking this syrup and seek medical advice.

Precautions:

Do not take Axalin® Expectorant more than 4 times in 24 hours.

Do not take Axalin® Expectorant in combination with any cold medication or cough suppressant.

Children under 6 years of age should be treated under medical supervision.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose.

Overdose

If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at a cool temperature between 15 and 20 degrees C (59 and 68 degrees F) and away from excess moisture and heat. Keep it tightly closed. Keep out of the reach of children.

Side effects

The most common side effects associated with the use of Axalin® Expectorant are:

  • headache
  • nervousness
  • dizziness
  • nausea and vomiting
  • dry mouth
  • sweating
  • allergic reactions
  • diarrhoea
  • abdominal pain
  • upset stomach

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Axalin® Expectorant if you are allergic to Ambroxol, Terbutaline or Guaiphenesin.

Do not take Axalin® Expectorant if you are allergic to any other ingredient comprised in this syrup.

Do not take Axalin® Expectorant if you have hypertrophic cardiomyopathy, hypokalemia or fructose intolerance.

Do not take Axalin® Expectorant in combination with beta-blocking agents (propranolol), sympathomimetics (epinephrine, norepinephrine, dopamine), halogenated anesthetics (halothane, isoflurane, enflurane, desflurane, sevoflurane), diuretics (amiloride, spironolactone, triamterene, eplerenone), methylxanthines (theophylline, dyphylline) and corticosteroids (prednisolone, beclometasone, fluticasone, hydrocortisone), monoamine oxidase inhibitors (rasagiline, selegiline, isocarboxazid, phenelzine, tranylcypromine), or tricyclic antidepressants (amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine).

Axalin® Expectorant should be used with caution in patients with acute severe asthma, thyrotoxicosis, cardiovascular disorders (ischemic heart disease, coronary insufficiency, cardiac arrhythmias, hypertension, severe heart failure), hyperthyroidism, peptic ulcers, diabetes mellitus, hypersensitivity to sympathomimetic amines, and convulsive disorders.

Do not give Axalin® Expectorant to children under 2 years of age.

Do not take Axalin® Expectorant during pregnancy and breastfeeding unless directed by your doctor.

Q: What is Axalin® Expectorant used for?

A: Axalin® Expectorant is an oral syrup used to relieve cough due bronchopulmonary disorders including bronchitis, bronchial asthma, and emphysema among others. Possesses muscle relaxing and secretolytic properties. Suitable for adults and children over 2 years of age.

Q: Is Axalin® Expectorant safe for my child?

A: Axalin® Expectorant is safe for children over 2 years of age, although it is recommended to consult your doctor prior to giving this syrup to children aged under 6 years. Always use this medication strictly according to instructions given.

Q: Can pregnant women take Axalin® Expectorant?

A: Do not take Axalin® Expectorant during pregnancy and breastfeeding unless directed by your doctor.

Target Point Shipping Method Tracking Delivery Time Price
Worldwide Shipping

Worldwide Shipping

Registered Mail  Not trackable 14-21 business days USD 15.00 per order
EMS  Trackable, where available 5-9 business days USD 25.00 per order

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Registered Mail - 14-21 business days, price - USD 15.00, no signature is required on delivery.
EMS - 5-9 business days, price - USD 25.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

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