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Ciprodex Ophthalmic and Otic Solution

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Ciprodex Ophthalmic and Otic Solution

Ciprodex ophthalmic and otic solution is used to treat bacterial infections in the eye(s) or ear(s) when caused by certain types of bacteria. Suitable for ophthalmic or otic use only, not for injection. Ciprodex ophthalmic and otic solution cannot be used in infants under 6 months old. Read more

Other names for this medication: Similar Products: Active Ingredient:

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Description

Ciprodex ophthalmic and otic solution contains two active ingredients Ciprofloxacin (second-generation Fluoroquinolone antibiotic) and Dexamethasone (synthetic member of the glucocorticoid class of steroid hormones), which allows to reduce itchiness, swelling or reddening while fighting and eliminating the infection.

Indications:

- bacterial eye infections (conjunctivitis, corneal ulcers, superficial infections of the eye and adnexa);

- bacterial ear infections (otitis externa, acute otitis media, chronic suppurative otitis media);

- alleviating infection symptoms such as irritation, itchiness, swelling or reddening;

- prophylaxis in otic surgeries such as mastoid surgery.

MOA (mechanism of action):

Ciprofloxacin is a synthetic antimicrobial agent that exhibits its bactericidal action through inhibiting the bacterial DNA gyrase enzyme, required for bacterial DNA replication, transcription, repair and recombination. Dexamethasone is a potent corticosteroid that effectively controls the inflammation by inhibiting the release inflammatory mediators. Namely, it involves phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.

Ciprofloxacin is effective against Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Serratia marcescens, Proteus mirabilis, Providencia rettgeri, Morganella morganii, Citrobacter diversus, Citrobacter freundii, Pseudomonas aeruginosa, Staphylococcus epidermidis and Streptococcus faecalis, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pyogenes, Campylobacter jejuni, Shigella flexneri and Shigella sonnei.

Dosage

For corneal ulcers: instill 2 drops into the treated eye every 15 minutes for the first 6 hours and then 2 drops into the treated eye every 30 minutes for the remainder of day 1.

Day 2: instill 2 drops in the treated eye hourly.

Day 3 - Day 14: instill 2 drops in the treated eye every 4 hours.

Treatment may be continued after 14 days if corneal re-epithelialization has not occurred.

For conjunctivitis: instill 1 or 2 drops instilled into the conjunctival sac(s) every 2 hours, while awake, for 2 days and 1 or 2 drops every 4 hours, while awake, for the next 5 days.

For superficial eye infection: instill 1 or 2 drops in the treated eye(s) 4 times a day. In severe infections, the dosage for the first 2 days may be 1 or 2 drops every 2 hours while awake.

The maximum duration of therapy of 21 days is recommended.

For ear infections: instill 2-3 drops every 2-3 hours initially, reducing the frequency of the instillation with control of infection.

Precautions:

Ciprodex ophthalmic and otic solution is associated with allergic reactions, even following a single dose. Discontinue using drops immediately and contact your physician at the first sign of a rash or allergic reaction.

Prolonged use of Ciprodex ophthalmic and otic solution may result in overgrowth of non-susceptible organisms, including fungi. If superinfection occurs, discontinue using these drops and institute alternative therapy.

Ciprodex ophthalmic and otic solution may cause your vision to blur temporarily after you have applied them into your eye. Do not drive or operate machinery until this has worn off.

Avoid contaminating the applicator tip with eye, fingers or another source.

Patients should not wear contact lenses while using Ciprodex ophthalmic and otic solution for eye infection.

Wash your hands before using the eye and ear drops.

Missing a dose

If you miss a dose you should instill it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not instill a double dose to make up for a missed one.

Overdose

If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately. A topical overdose of Ciprodex ophthalmic and otic solution may be flushed from the eye(s) with lukewarm tap water.

Storage

Store at cool room temperature not exceeding 30 C degrees, away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use. Use within one month after opening a container. Keep out of the reach of children.

Side effects

The most common side effects associated with Ciprodex ophthalmic and otic solution are:

  • blurred vision
  • irritation
  • stinging sensations
  • increased light sensitivity
  • headaches
  • dizziness

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Ciprodex ophthalmic and otic solution in infants under 6 months old.

Do not use Ciprodex ophthalmic and otic solution if you are allergic to Ciprofloxacin, Dexamethasone, to other Fluoroquinolones and Corticosteroids.

Do not use Ciprodex ophthalmic and otic solution if you are allergic to any ingredient comprised in Ciprodex ophthalmic and otic solution.

Do not use Ciprodex ophthalmic and otic solution if you have a history of severe allergic reactions associated with using antibiotics.

Do not use Ciprodex ophthalmic and otic solution if you have viral infections of the external (herpes simplex infections), fungal otic infections, glaucoma, cataract.

Do not use Ciprodex ophthalmic and otic solution in combination with products or medications containing caffeine, anticoagulants (warfarin), cyclosporines.

Patients should not wear contact lenses while using Ciprodex ophthalmic and otic solution for eye infection.

Consult your doctor before using Ciprodex ophthalmic and otic solution if you are pregnant, plan to have a baby or are breastfeeding.

Q: What is Ciprodex ophthalmic and otic solution used for?

A: Ciprodex ophthalmic and otic solution is used to treat bacterial infections in the eye(s) or ear(s) when caused by certain types of bacteria. Suitable for ophthalmic or otic use only, not for injection. Ciprodex ophthalmic and otic solution cannot be used in infants under 6 months old.

Q: Is Ciprodex ophthalmic and otic solution safe?

A: Ciprodex ophthalmic and otic solution is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Q: Can I use Ciprodex ophthalmic and otic solution for a fungal infection?

A: Ciprodex ophthalmic and otic solution will not work for viral infections and for infections caused by mycoses (fungi).

Target Point Shipping Method Tracking Delivery Time Price
Worldwide Shipping

Worldwide Shipping

Registered Mail  Not trackable 14-21 business days USD 15.00 per order
EMS  Trackable, where available 5-9 business days USD 25.00 per order

Delivery time is:

Registered Mail - 14-21 business days, price - USD 15.00, no signature is required on delivery.
EMS - 5-9 business days, price - USD 25.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

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