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About Methiz®

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Description

Methiz® is produced by Concern Pharma with the active ingredient Promethazine — a first-generation H1-receptor antagonist, antihistamine and antiemetic medication with potent sedative effects.

Indications:

- to treat insomnia in adults (for short-term use);

- to treat allergies due to hay fever or rashes (nettle rash or hives);

- to treat or stop nausea or vomiting (travel sickness);

- to use as a sedative for children aged 5 years and above (for short-term use).

MOA (mechanism of action):

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine inhibits the action of endogenous histamine, which subsequently leads to temporary relief of the negative allergic symptoms. The relief of nausea appears to be related to central anticholinergic actions and may implicate activity on the medullary chemoreceptor trigger zone.

Dosage

For allergies (such as hay fever, rashes, and hives)

Children 5-10 years: 1 tablet (25 mg) given at bedtime.

Do not give more than 25 mg per day.

Children over 10 years and adults (including the elderly): initially 1 tablet (25 mg) taken at bedtime.

This may be increased to a maximum of 1 tablet (25 mg) twice a day if necessary.

For treatment and prevention of feeling sick or being sick (such as travel sickness)

Children 5-10 years: promethazine elixir or Promethazine 10 mg tablets should be given in this age group.

Children over 10 years and adults (including the elderly): 1 tablet (25 mg) to be taken the night before the journey.

This may be repeated after 6-8 hours if necessary.

For short-term pediatric sedative and for short-term treatment of insomnia in adults

Children 5-10 years: 1 tablet (25 mg) given at bedtime.

Children over 10 years and adults (including the elderly): 1 or 2 tablets (25 mg - 50 mg) taken at bedtime.

Missing a dose

If you miss a dose you should spray it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not spray a double dose of Methiz® to compensate the missed dose.

Overdose

If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature below 30 degrees C away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

Common and uncommon side effects associated with Methiz® are:

  • tardive dyskinesia
  • confusion in the elderly
  • drowsiness
  • dizziness
  • fatigue
  • dry mouth
  • constipation
  • chest discomfort/pressure
  • akathisia
  • paresthesia
  • short temper/irritability
  • blurred vision
  • dry mouth
  • dilated pupils
  • nausea
  • urinary retention (inability to urinate)
  • impotence
  • constipation

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Methiz® if you are allergic to Promethazine or any ingredients comprised in this medication.

Do not take Methiz® if you suffer from epilepsy, have difficulty breathing, wheezing, tightness in the chest (asthma) or an infection in your lungs (bronchitis), serious heart problems, liver or kidney problems, a stomach blockage or difficulty passing water, hearing problems, narrow-angle glaucoma, Reye’s Syndrome or signs of Reye’s Syndrome.

Do not take Methiz® in person is unconscious (in a coma) or suffers from severe dizziness, drowsiness or headache.

Do not combine Methiz® with oral drugs for diabetes, drugs to treat sleeplessness or anxiety, other antihistamines to treat allergic reactions, drugs for depression called a monoamine oxidase inhibitor (MAOI), aspirin (for arthritis and pain in your joints), drugs to help you to sleep or feel more relaxed (such as diazepam or zolpidem), anticholinergic drugs.

Do not drink alcohol when you are taking Methiz®.

Do not take Methiz® if you are pregnant unless prescribed, plan to have a baby or are breastfeeding.

Methiz® is not for use in children under 5 years of age.

Q: What is Methiz® used for?

A: Methiz® is indicated to treat symptoms of allergy like rash and hives, treat sleeplessness, nausea, and vomiting. The medication can also be used as a sedative for children aged 5 years and above. Not for use in pediatric patients under 5 years of age.

Q: Is Methiz® safe?

A: Yes. Methiz® is safe if used as directed by your physician.

Q: What if I forget to take the tablet?

A: If you are taking Methiz® tablets for an allergic condition — take your medicine as soon as you remember, then carry on as before.

Target Point Shipping Method Tracking Delivery Time Price
Worldwide Shipping

Worldwide Shipping

Registered Mail  Not trackable 14-21 business days USD 20.00 per order
EMS  Trackable, where available 5-9 business days USD 30.00 per order

Delivery time is:

Registered Mail - 14-21 business days, price - USD 20.00, no signature is required on delivery.
EMS - 5-9 business days, price - USD 30.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

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